1-[5-bromo-6-[(1S)-1-methoxyethyl]-3-pyridyl]-4-methyl-piperazine (CAS No: 2940879-42-3) is a key pharmaceutical intermediate used in the synthesis of APIs Daraxonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (S)-1-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-4-methylpiperazine, (S)-1-[5-Bromo-6-(1-methoxyethyl)-3-pyridyl]-4-methylpiperazine
CAS No: 2940879-42-3
PubChem CID: 167483950
Mol Formula: C13H20BrN3O
Mol Weight: 314.22 g/mol
Used in API: Daraxonrasib
IUPAC Name: 1-[5-bromo-6-[(1S)-1-methoxyethyl]-3-pyridinyl]-4-methylpiperazine
API Intermediate Description: Daraxonrasib (RMC-6236) is a RAS inhibitor, and 1-[5-bromo-6-[(1S)-1-methoxyethyl]-3-pyridyl]-4-methylpiperazine is a chiral bromopyridine intermediate used in its synthesis. The bromine substituent provides a reactive site for subsequent cross-coupling or other functionalization, while the (S)-1-methoxyethyl group and N-methylpiperazine moiety contribute to the required structural and stereochemical features. Further coupling and functional-group transformations of this intermediate help construct the advanced scaffold leading to daraxonrasib.
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