tert-Butyl (S)-4-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)piperazine-1-carboxylate (CAS No: 2641824-76-0) is a key pharmaceutical intermediate used in the synthesis of APIs Daraxonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: tert-butyl 4-[5-bromo-6-[(1S)-1-methoxyethyl]pyridin-3-yl]piperazine-1-carboxylate
CAS No: 2641824-76-0
PubChem CID: 156312223
Mol Formula: C17H26BrN3O3
Mol Weight: 400.3 g/mol
Used in API: Daraxonrasib
IUPAC Name: tert-butyl 4-[5-bromo-6-[(1S)-1-methoxyethyl]-3-pyridinyl]piperazine-1-carboxylate
API Intermediate Description: Daraxonrasib (RMC-6236) is a RAS inhibitor, and tert-butyl (S)-4-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)piperazine-1-carboxylate is an advanced chiral intermediate used in its synthesis. It contains the bromopyridine moiety for subsequent cross-coupling and the Boc-protected piperazine group, while the (S)-1-methoxyethyl substituent provides the required stereochemical element. Further coupling, deprotection, and functional-group transformations of this intermediate help assemble the advanced molecular framework leading to the daraxonrasib API.
