3-Bromo-5-fluoropicolinonitrile (CAS No: 950670-18-5) is a key pharmaceutical intermediate used in the synthesis of APIs Daraxonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 3-Bromo-5-fluoropyridine-2-carbonitrile, 3-Bromo-2-cyano-5-fluoropyridine
CAS No: 950670-18-5
PubChem CID: 46941477
Mol Formula: C6H2BrFN2
Mol Weight: 201.00 g/mol
Used in API: Daraxonrasib
IUPAC Name: 3-bromo-5-fluoropyridine-2-carbonitrile
API Intermediate Description: Daraxonrasib (RMC-6236) is a RAS inhibitor, and 3-bromo-5-fluoropicolinonitrile is a halogenated pyridine intermediate used in the synthesis of advanced daraxonrasib intermediates. Its bromo and fluoro substituents provide useful handles for selective functionalization and cross-coupling, while the nitrile group serves as an important functional group for subsequent transformations. Further coupling and structural modifications of this intermediate help construct the substituted pyridine framework present in the daraxonrasib API.
