Methyl (S)-Hexahydropyridazine-3-carboxylate Hydrochloride (CAS No: 380223-17-6) is a key pharmaceutical intermediate used in the synthesis of APIs Daraxonrasib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (S)-Methyl hexahydropyridazine-3-carboxylate hydrochloride, Methyl (3S)-hexahydropyridaZine-3-carboxylate hydrochloride
CAS No: 380223-17-6
PubChem CID: 66846189
Mol Formula: C6H13ClN2O2
Mol Weight: 180.63 g/mol
Used in API: Daraxonrasib
IUPAC Name: methyl (3S)-diazinane-3-carboxylate;hydrochloride
API Intermediate Description: Daraxonrasib (RMC-6236) is a RAS inhibitor, and methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride is a chiral intermediate used in its synthesis. It provides the (S)-hexahydropyridazine-3-carboxylate building block and serves as a key coupling partner for introducing the required pyridazine-containing portion of the molecule. Subsequent acylation, deprotection, and coupling reactions of this intermediate contribute to the construction of advanced intermediates leading to the final daraxonrasib API.
