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Alternate Names: Dopram, Stimulexin
CAS No: 113-07-5
PubChem CID: 64647
Mol Formula: C24H31ClN2O2
Mol Weight: 415.0 g/mol
IUPAC Name: 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one;hydrochloride
API Description: Doxapram Hydrochloride is a peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in the carotid arteries and, at increased dosage, stimulates central respiratory centers in the medulla as well as other parts of the brain and spinal cord. This results in an increased tidal volume and a slightly increased respiratory rate. Doxapram hydrochloride may also improve cardiac output probably due to an increased release of catecholamines. This respiratory stimulant is used in postanesthesia respiratory depression.
