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Alternate Names: 4-Aminomethylbenzenesulfonamide hydrochloride,Homosulfamine hydrochloride
CAS No: 49783-80-4
PubChem CID: 67313
Mol Formula: C7H11ClN2O2S
Mol Weight: 222.69 g/mol
IUPAC Name: 4-(aminomethyl)benzenesulfonamide;hydrochloride
Commercial / Development Status: Unknown/Inactive APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Mafenide Hydrochloride is a synthetic sulfonamide-derived antibacterial agent used primarily in the prevention and treatment of infections in severe burn wounds. It exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, a common pathogen in burn-related infections. The drug acts by inhibiting bacterial folic acid synthesis, thereby preventing bacterial growth. Due to its ability to penetrate burn eschar effectively, it is particularly valuable in managing deep or extensive burns where other topical antibiotics may be less effective.
