3-Methyl-1-(2-piperidinophenyl)-1-butylamine, (S)-, N-acetyl-L-glutamate (CAS No: 219921-94-5) is a key pharmaceutical intermediate used in the synthesis of APIs Repaglinide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: L-Glutamic acid, N-acetyl-, compd. with (.alpha.S)-.alpha.-(2-methylpropyl)-2-(1-piperidinyl)benzenemethanamine (1:1) (9CI), (1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butan-1-amine N-acetyl-L-glutamate
CAS No: 219921-94-5
PubChem CID: 56965742
Mol Formula: C23H37N3O5
Mol Weight: 435.6 g/mol
Used in API: Repaglinide
IUPAC Name: (2S)-2-acetamidopentanedioic acid;(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butan-1-amine
API Intermediate Description: (S)-3-Methyl-1-(2-piperidinophenyl)butylamine N-acetyl-L-glutamate is a key chiral intermediate used in the synthesis of Repaglinide, an oral anti-diabetic drug. It acts as a stable, optically pure salt for the (S)-amine, which is condensed with 4-ethoxycarbonyl-3-ethoxyphenylacetic acid, followed by hydrolysis to yield the final API.
