(2R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid (CAS No: 129101-37-7) is a key pharmaceutical intermediate used in the synthesis of APIs Nebivolol. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (R)-6-Fluorochroman-2-carboxylic acid, 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2R)-
CAS No: 129101-37-7
PubChem CID: 28242420
Mol Formula: C10H9FO3
Mol Weight: 196.17 g/mol
Used in API: Nebivolol
IUPAC Name: (2R)-6-fluoro-3,4-dihydro-2H-chromene-2-carboxylic acid
API Intermediate Description: (2R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid is a critical chiral building block (starting material) in the synthesis of Nebivolol, specifically for the [R, S, S, S] isomer. It is converted into (R)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxaldehyde, which is then reduced/oxidized into essential epoxides.
