Darifenacin_dealkyl_tartrate (CAS No: 134002-26-9) is a key pharmaceutical intermediate used in the synthesis of APIs Darifenacin. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Darifenacin intermediate IV, (S)-3-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine L-tartrate
CAS No: 134002-26-9
PubChem CID: 24968963
Mol Formula: C22H26N2O7
Mol Weight: 430.5 g/mol
Used in API: Darifenacin
IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid;2,2-diphenyl-2-[(3S)-pyrrolidin-3-yl]acetamide
API Intermediate Description: Darifenacin alkyl tartrate—specifically, 3-(S)-(+)-(1-carbamoyl-1,1-diphenylmethyl)pyrrolidine L-(+)-tartrate—is used as a key intermediate salt in the synthesis of Darifenacin (an M3 receptor antagonist for overactive bladder) to enhance optical purity and facilitate crystallization, thereby avoiding tedious column chromatography. It serves as the chiral, stable precursor that is reacted with 5-(2-bromoethyl)-2,3-dihydrobenzofuran or 5-(2-tosyloxyethyl)-2,3-dihydrobenzofuran to produce high-purity Darifenacin.
