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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate (CAS No: 125995-13-3) API Intermediate Manufacturers

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate (CAS No: 125995-13-3) is a key pharmaceutical intermediate used in the synthesis of APIs Atorvastatin. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

Alternate Names: 1,1-Dimethylethyl (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate, Atorvastatin Impurity 83

CAS No: 125995-13-3

PubChem CID: 2734288

Mol Formula: C14H27NO4

Mol Weight: 273.37 g/mol

Used in API: Atorvastatin

IUPAC Name: tert-butyl 2-[(4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate

API Intermediate Description: (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is a critical chiral side-chain intermediate (side-chain amine) used in the synthesis of Atorvastatin calcium. It provides the essential 3,5-dihydroxy carboxylic acid moiety (protected as a dioxane) required for inhibiting HMG-CoA reductase.

                   
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

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