2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide (CAS No: 302964-08-5) is a key pharmaceutical intermediate used in the synthesis of APIs Dasatinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-
CAS No: 302964-08-5
PubChem CID: 11269410
Mol Formula: C16H13Cl2N5OS
Mol Weight: 394.3 g/mol
Used in API: Dasatinib
IUPAC Name: N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide
API Intermediate Description: 2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide is a key intermediate in the synthesis of Dasatinib, a tyrosine kinase inhibitor. It serves as a penultimate precursor that reacts with 1-(2-hydroxyethyl)piperazine to introduce the piperazine side chain, completing the molecule.
![2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=11269410&t=l)
