(Methoxymethyl)triphenylphosphonium chloride (CAS No: 4009-98-7) is a key pharmaceutical intermediate used in the synthesis of APIs Acitretin and Tofacitinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Phosphonium, (methoxymethyl)triphenyl-, chloride;, methoxymethyltriphenylphosphorane
CAS No: 4009-98-7
PubChem CID: 2723799
Mol Formula:C20H20OP+
Mol Weight: 307.3 g/mol
Used in APIs: Acitretin and Tofacitinib
IUPAC Name: methoxymethyl(triphenyl)phosphanium
API Intermediate Description: (Methoxymethyl)triphenylphosphonium chloride is used as a synthetic reagent in the preparation of Tofacitinib. It functions as a precursor to a Wittig reagent that enables carbon–carbon double bond formation through an olefination reaction with a suitable carbonyl compound. This reaction helps build an important structural fragment required for the molecule. After this step, the product undergoes further chemical transformations such as reduction, substitution, or deprotection steps during the manufacturing process, ultimately leading to the formation of the final Active Pharmaceutical Ingredient.
