(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one (CAS No: 139893-81-5) is a key pharmaceutical intermediate used in the synthesis of APIs Edoxaban. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: SCHEMBL15741154
CAS No: 139893-81-5
PubChem CID: 76282756
Mol Formula: C7H9BrO2
Mol Weight: 205.05 g/mol
Used in API: Edoxaban
IUPAC Name: (1S,4S,5S)-4-bromo-6-oxabicyclo[3.2.1]octan-7-one
API Intermediate Description: (1S,4S,5S)-4-Bromo-6-oxabicyclooctan-7-one is a critical, chiral, bicyclic intermediate used in the synthesis of the FXa inhibitor edoxaban. It is employed to construct the specific stereochemistry of the cyclohexane diamine core by undergoing ring-opening and subsequent functionalization, such as in the preparation of tert-butyl (1R,2S,5S)-2-amino-5-(dimethylcarbamoyl)cyclohexylcarbamate.
![(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=76282756&t=l)
