2,6-Difluorobenzyl chloride (CAS No: 697-73-4) is a key pharmaceutical intermediate used in the synthesis of APIs Rufinamide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: alpha-Chloro-2,6-difluorotoluene, Toluene, alpha-chloro-2,6-difluoro-
CAS No: 697-73-4
PubChem CID: 581570
Mol Formula: C7H5ClF2
Mol Weight: 162.56 g/mol
Used in API: Rufinamide
IUPAC Name: 2-(chloromethyl)-1,3-difluorobenzene
API Intermediate Description: 2,6-Difluorobenzyl chloride is a crucial starting material for synthesizing Rufinamide, an anticonvulsant drug, serving as the source for the difluorobenzyl group, typically converted to 2,6-difluorobenzyl azide which then undergoes cycloaddition with an alkyne (like propiolic acid derivatives) to form the 1,2,3-triazole ring core of Rufinamide through Click chemistry. This key intermediate introduces the characteristic difluorobenzyl moiety, essential for Rufinamide's therapeutic action in treating Lennox-Gastaut syndrome seizures.
