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Alternate Names: Vizimpro, 2-Butenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-, (2E)-
CAS No: 1110813-31-4
PubChem CID: 11511120
Mol Formula: C24H25ClFN5O2
Mol Weight: 469.95 g/mol
IUPAC Name: (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
API Description: Dacomitinib is an irreversible pan-human epidermal growth factor receptor (HER) tyrosine kinase inhibitor used in the treatment of metastatic non-small cell lung cancer (NSCLC) with EGFR mutations. It binds covalently to the kinase domain of EGFR, inhibiting its activity.
