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Alternate Names: Neoral, Sandimmune, Neoplanta, Cyclosporine
CAS No: 59865-13-3
PubChem CID: 5284373
Mol Formula: C62H111N11O12
Mol Weight: 1202.6 g/mol
IUPAC Name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2- -Show More
Therapeutic use: Anti-inflammatories, Anti-psoriatic agents, Antirheumatic Agents, Ophthalmic Agents
Drug Class: Calcineurin inhibitors, Immunosuppressants
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Fermentation-derived APIs
API Description: Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. It has a role as an antifungal agent, an antirheumatic drug, a dermatologic drug, an immunosuppressive agent, a metabolite, a carcinogenic agent, an anti-asthmatic drug, an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor, an anticoronaviral agent and a geroprotector.
