methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate (CAS No: 865774-07-8) is a key pharmaceutical intermediate used in the synthesis of APIs Nirogacestat. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1H-Imidazole-1-acetic acid, alpha,alpha-dimethyl-4-nitro-, methyl ester;, 2-Methyl-2-(4-nitro-imidazol-1-yl)-propionic acid methyl ester
CAS No: 865774-07-8
PubChem CID: 67164903
Mol Formula: C8H11N3O4
Mol Weight: 213.19 g/mol
Used in API: Nirogacestat
IUPAC Name: methyl 2-methyl-2-(4-nitroimidazol-1-yl)propanoate
API Intermediate Description: Methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate is a key building block or intermediate in the synthesis of Nirogacestat, providing the core 4-nitroimidazole scaffold with the required propanoate side chain, often converted to the corresponding propanoic acid or aldehyde (like 2-Methyl-2-(4-nitro-1H-imidazol-1-yl)propanal) for subsequent coupling to form the complex Nirogacestat molecule, a gamma-secretase inhibitor.
