2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile (CAS No: 763114-25-6) is a key pharmaceutical intermediate used in the synthesis of APIs Olaparib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Olaparib impurity 142, 3-(3-cyano-4-fluorobenzylidene)isobenzofuran-1(3H)-one
CAS No: 763114-25-6
PubChem CID: 67122451
Mol Formula: C16H8FNO2
Mol Weight: 265.24 g/mol
Used in API: Olaparib
IUPAC Name: 2-fluoro-5-[(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile
API Intermediate Description: 2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile (CAS 763114-25-6) is a crucial intermediate or building block in the multi-step synthesis of Olaparib (Lynparza), a targeted cancer drug (PARP inhibitor). It provides part of the core structure, specifically incorporating the benzonitrile and phthalide/phthalazinone precursor elements, which are then further modified (e.g., via reactions like Negishi coupling) to form the final complex Olaparib molecule.
