4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one (CAS No: 91526-18-0) is a key pharmaceutical intermediate used in the synthesis of APIs Azilsartan medoxomil. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Olmesartan metabolite RNH-8097, 1,3-Dioxol-2-one, 4-(hydroxymethyl)-5-methyl-
CAS No: 91526-18-0
PubChem CID: 10510878
Mol Formula: C5H6O4
Mol Weight: 130.10 g/mol
Used in API: Azilsartan medoxomil
IUPAC Name: 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one
API Intermediate Description: 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one (DMDO-OH) is primarily used in organic synthesis as a key intermediate, especially for creating prodrugs to improve drug delivery, most notably in antihypertensive drugs like Azilsartan medoxomil, by adding a bioreversible carbamate group that enhances bioavailability before being cleaved in the body. It also serves as a versatile building block for synthesizing complex molecules and exploring new materials, including certain polymers and fine chemicals, by allowing for precise structural modifications.