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Alternate Names: Aprotinin, Bovine Aprotinin
CAS No: 9087-70-1
PubChem CID: 16130295
Mol Formula: C284H432N84O79S7
Mol Weight: 6511 g/mol
IUPAC Name: (3S)-4-[[(2S)-1-[[(1R,2aS,4S,5aS,8aS,11aS,13S,14aS,16S,17aR,19S,20aS,25S,26aS,29aS,31S,32aS,34S,35aS,37R,38aS,41aS,42R,44aS,45S,47aS,48S,50aS,51S,53aS -Show More
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Biotechnology APIs
API Description: Aprotinin is a polypeptide protease inhibitor and a biologically derived active pharmaceutical ingredient (API). It consists of a single-chain basic polypeptide with 58 amino acids and acts as a broad-spectrum inhibitor of serine proteases, including trypsin, plasmin, and kallikrein. Aprotinin exerts its pharmacological effect by reversibly binding to proteolytic enzymes, thereby inhibiting fibrinolysis and reducing excessive protease activity. This mechanism results in reduced bleeding and blood loss, particularly during surgical procedures.
