L-Proline, N-(methoxycarbonyl)-L-valyl-5-methyl-, (5S)- (CAS No: 1335316-40-9) is a key pharmaceutical intermediate used in the synthesis of APIs Velpatasvir. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (2S,5S)-1-((S)-2-((Methoxycarbonyl)amino)-3-methylbutanoyl)-5-methylpyrrolidine-2-carboxylic acid,(5S)-N-(Methoxycarbonyl)-L-valyl-5-methyl-L-proline
CAS No: 1335316-40-9
PubChem CID: 67412687
Mol Formula: C13H22N2O5
Mol Weight: 286.32 g/mol
Used in API: Velpatasvir
IUPAC Name: (2S,5S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-5-methylpyrrolidine-2-carboxylic acid
API Intermediate Description: L-Proline, N-(methoxycarbonyl)-L-valyl-5-methyl-, (5S)- is a protected dipeptide derivative used as a synthetic intermediate in peptide and medicinal chemistry.It comprises an L-valine residue linked via an amide bond to 5-methyl-L-proline, with the N-terminus protected as a methoxycarbonyl (carbamate). The defined (5S) stereochemistry preserves the conformational preferences of the proline ring, which is critical for controlling backbone geometry in downstream synthesis.
