1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one (CAS No: 196597-78-1) is a key pharmaceutical intermediate used in the synthesis of APIs Ramelteon. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1,2,6,7-tetrahydrocyclopenta[e]benzofuran-8-one,1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one
CAS No: 196597-78-1
PubChem CID: 11137616
Mol Formula: C11H10O2
Mol Weight: 174.20 g/mol
Used in API: Ramelteon
IUPAC Name: 1,2,6,7-tetrahydrocyclopenta[e][1]benzofuran-8-one
API Intermediate Description: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one is a fused bicyclic lactone used primarily as a synthetic intermediate in organic and medicinal chemistry. It consists of an indan-derived framework fused with a furanone (lactone) ring, partially hydrogenated to give a rigid yet reactive structure. The lactone carbonyl provides an electrophilic center suitable for ring-opening, reduction, or condensation reactions, while the fused bicyclic system offers conformational rigidity valuable in scaffold design.
![1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=11137616&t=l)
