1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one (CAS No: 63106-93-4) is a key pharmaceutical intermediate used in the synthesis of APIs Milnacipran. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one,2-Oxo-1-phenyl-3-oxabicyclo[3.1.0]-hexane
CAS No: 63106-93-4
PubChem CID: 11745119
Mol Formula: C11H10O2
Mol Weight: 174.20 g/mol
Used in API: Milnacipran
IUPAC Name: 1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one
API Intermediate Description: 1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one is a strained bicyclic lactone used as a synthetic intermediate in organic and medicinal chemistry. It features a compact oxabicyclic framework incorporating a lactone (cyclic ester) functionality fused to a cyclopropane-like ring, with a phenyl substituent that adds aromatic character and stability. The inherent ring strain and electrophilic carbonyl group make the molecule highly reactive toward ring-opening, nucleophilic addition, and rearrangement reactions.
![1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=11745119&t=l)
