7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one (CAS No: 137982-91-3) is a key pharmaceutical intermediate used in the synthesis of APIs Tolvaptan. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Tolvaptan Intermediate 3, 5H-1-Benzazepin-5-one, 7-chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-
CAS No: 137982-91-3
PubChem CID: 19608065
Mol Formula: C18H15ClN2O4
Mol Weight: 358.8 g/mol
Used in API: Tolvaptan
IUPAC Name: 7-chloro-1-(2-methyl-4-nitrobenzoyl)-3,4-dihydro-2H-1-benzazepin-5-one
API Intermediate Description: 7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one is primarily used as a crucial intermediate in synthesizing Tolvaptan, a medication for low sodium levels (hyponatremia) from heart failure or cirrhosis and SIADH, acting as a vasopressin V2 receptor antagonist. It's also a valuable heterocyclic building block in pharmaceutical research, particularly for developing new neuroactive drugs targeting dopamine receptors for conditions like depression or Parkinson's, leveraging its core benzazepine structure.
