N-Carbobenzoyl-DL-valine (CAS No: 3588-63-4) is a key pharmaceutical intermediate used in the synthesis of APIs Valganciclovir. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: DL-Cbz-Valine, Valine, N-[(phenylmethoxy)carbonyl]-
CAS No: 3588-63-4
PubChem CID: 97743
Mol Formula: C13H17NO4
Mol Weight: 251.28 g/mol
Used in API: Valganciclovir
IUPAC Name: 3-methyl-2-(phenylmethoxycarbonylamino)butanoic acid
API Intermediate Description: N‑Carbobenzoyl‑DL‑valine (N‑CBZ‑DL‑valine) is a protected amino acid derivative commonly used as a chemical intermediate in pharmaceutical synthesis. Its carbobenzoyl (CBZ) group protects the amino functionality of valine during chemical reactions, allowing selective transformations without unwanted side reactions. One notable application of N‑Carbobenzoyl‑DL‑valine is in the synthesis of valganciclovir, an antiviral prodrug used to treat cytomegalovirus (CMV) infections. In this pathway, N‑CBZ‑DL‑valine serves as a valine ester intermediate, which is later converted into the final API, valganciclovir, after deprotection and other reaction steps. Beyond valganciclovir, N‑Carbobenzoyl‑DL‑valine is also widely used in the synthesis of other peptide-based APIs or compounds where introduction of a valine unit is required.
