2-Ethoxyethyl 4-methylbenzene-1-sulfonate (CAS No: 17178-11-9) is a key pharmaceutical intermediate used in the synthesis of APIs Bilastine. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (2-ethoxy)ethyl p-toluenesulphonate, p-toluenesulfonic-acid-(2-ethoxyethyl)-ester
CAS No: 17178-11-9
PubChem CID: 4125390
Mol Formula: C11H16O4S
Mol Weight: 244.31 g/mol
Used in API: Bilastine
IUPAC Name: 2-ethoxyethyl 4-methylbenzenesulfonate
API Intermediate Description: 2-Ethoxyethyl 4-methylbenzene-1-sulfonate is a key intermediate, primarily used in the synthesis of the second-generation antihistamine Bilastine, which treats allergies like hay fever (allergic rhinitis) and hives (urticaria). This compound acts as a versatile building block, introducing the necessary ethoxyethyl group and serving as a protecting group for hydroxyls or as a good leaving group in nucleophilic substitutions during Bilastine's complex multi-step manufacturing process, ensuring high yield and purity.