Chloromethyl isopropyl carbonate (CAS No: 35180-01-9) is a key pharmaceutical intermediate used in the synthesis of APIs Tenofovir Disoproxil Fumarate. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Carbonic acid, chloromethyl 1-methylethyl ester; Chloromethylisopropylcarbonate
CAS No: 35180-01-9
PubChem CID: 14787051
Mol Formula: C5H9ClO3
Mol Weight: 152.57 g/mol
Used in API: Tenofovir Disoproxil Fumarate
IUPAC Name: chloromethyl propan-2-yl carbonate
API Intermediate Description: Chloromethyl isopropyl carbonate (CMIC) is a key organic intermediate primarily used in the pharmaceutical industry to synthesize antiviral drugs like Tenofovir, which treats HIV and Hepatitis B, acting as a building block in its complex chemical production. It's a versatile reagent for making other fine chemicals, but its presence as a potential mutagenic impurity in Tenofovir formulations has raised significant health concerns and regulatory scrutiny from bodies like the World Health Organization (WHO).