N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine (CAS No: 444731-74-2) is a key pharmaceutical intermediate used in the synthesis of APIs Pazopanib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole, Pazopanib Impurity 24
CAS No: 444731-74-2
PubChem CID: 11637631
Mol Formula: C13H12ClN5
Mol Weight: 273.72 g/mol
Used in API: Pazopanib
IUPAC Name: N-(2-chloropyrimidin-4-yl)-2,3-dimethylindazol-6-amine
API Intermediate Description: N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine is primarily used as a pharmaceutical impurity, intermediate, and reference standard in the development and quality control of the anti-cancer drug Pazopanib, a tyrosine kinase inhibitor (TKI) for treating renal cell carcinoma and soft tissue sarcoma. Its main role is to help identify, quantify, and control potential impurities during Pazopanib's manufacturing process, ensuring the drug's safety and efficacy, rather than being a therapeutic agent itself.
