2-Oxindole-6-carboxylic acid methyl ester (CAS No: 14192-26-8) is a key pharmaceutical intermediate used in the synthesis of APIs Nintedanib esylate and Nintedanib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Methyl 2-oxoindoline-6-carboxylate, Nintedanib Impurity 72
CAS No: 14192-26-8
PubChem CID: 3734372
Mol Formula: C10H9NO3
Mol Weight: 191.18 g/mol
Used in APIs: Nintedanib esylate and Nintedanib
IUPAC Name: methyl 2-oxo-1,3-dihydroindole-6-carboxylate
API Intermediate Description: 2-Oxindole-6-carboxylic acid methyl ester is a key chemical building block, primarily used in the pharmaceutical industry as an intermediate for synthesizing drugs, especially cancer treatments like BIBF 1120 (Nintedanib), a multi-targeted angiokinase inhibitor. It also serves as a versatile component in organic synthesis, helping create complex molecules for research in areas like neurological disorders, enzyme inhibition, and advanced materials.
