Boc-L-His(Boc)-Aib-OH (CAS No: 1169630-98-1) is a key pharmaceutical intermediate used in the synthesis of APIs Semaglutide. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: N-alpha-t-Butyloxycarbonyl-L-histidyl-Nim-t-butyloxycarbonyl-aminoisobutyric acid (Boc-L-His(Boc)-Aib-OH), Boc-L-His(Boc)-Aib-OH (N-Boc-L-Histidine(N-Boc)-Aib-OH)
CAS No: 1169630-98-1
PubChem CID: 59616500
Mol Formula: C20H32N4O7
Mol Weight: 440.5 g/mol
Used in API: Semaglutide
IUPAC Name: 2-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[3-[(2-methylpropan-2-yl)oxycarbonyl]imidazol-4-yl]propanoyl]amino]propanoic acid
API Intermediate Description: Boc-L-His(Boc)-Aib-OH is a protected dipeptide derivative consisting of Boc-protected L-histidine and α-aminoisobutyric acid (Aib). The dual Boc groups protect the amino and imidazole functionalities, making it useful as an intermediate in peptide synthesis. It is commonly used in solid-phase peptide assembly to introduce Aib-containing motifs that promote helical structures.
