N-Boc-sitagliptin (CAS No: 486460-23-5) is a key pharmaceutical intermediate used in the synthesis of APIs Sitagliptin phosphate. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Sitagliptin N-Boc Impurity, Sitagliptin Impurity 22
CAS No: 486460-23-5
PubChem CID: 46836576
Mol Formula: C21H23F6N5O3
Mol Weight: 507.4 g/mol
Used in API: Sitagliptin phosphate
IUPAC Name: tert-butyl N-[(2R)-4-oxo-4-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]carbamate
API Intermediate Description: N-Boc-sitagliptin is a protected form of sitagliptin, where the amino group is masked with a tert-butoxycarbonyl (Boc) group. This intermediate is widely used in the synthesis of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type 2 diabetes, allowing selective reactions without affecting the free amine.
