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Alternate Names: Glycinamide, N-acetyl-3-mercapto-L-valyl-L-asparaginyl-L-threonyl-7-methyl-L-tryptophyl-N6-acetyl-L-lysyl-3-mercapto-L-valyl-O-(2-aminoethyl)-L-tyrosyl-3-(2-naphthalenyl)-L-alanyl-4-aminotetrahydro-2H-pyran-4-carbonyl-L-alpha-glutamyl-L-asparaginyl-3-(3-pyridinyl)-L-alanyl-N2-methyl-, cyclic (1-->6)-disulfide
CAS No: 2763602-16-8
PubChem CID: 162462321
Mol Formula: C90H120N20O22S2
Mol Weight: 1898.2 g/mol
IUPAC Name: (4S)-4-[[4-[[(2S)-2-[[(2S)-2-[[(4R,7S,10S,13S,16S,19R)-19-acetamido-7-(4-acetamidobutyl)-16-(2-amino-2-oxoethyl)-13-[(1R)-1-hydroxyethyl]-3,3,20,20-t -Show More
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Peptide APIs
API Description: Icotrokinra is an investigational oral peptide drug used to treat moderate-to-severe plaque psoriasis, with potential for other inflammatory diseases like ulcerative colitis and psoriatic arthritis. It works by blocking the IL-23 receptor, which plays a role in these inflammatory conditions. Clinical trials have shown it to be effective for clearing skin, even in hard-to-treat areas like the scalp and genitals, and it is being studied as a next-generation alternative to injectable biologics.
