5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione (CAS No: 144809-28-9) is a key pharmaceutical intermediate used in the synthesis of APIs Pioglitazone. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: (E)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione, Pioglitazone Impurity 6
CAS No: 144809-28-9
PubChem CID: 14211277
Mol Formula: C19H18N2O3S
Mol Weight: 354.4 g/mol
Used in API: Pioglitazone
IUPAC Name: (5E)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
API Intermediate Description: 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione is a thiazolidinedione derivative featuring a benzylidene moiety substituted with a 2-(5-ethyl-2-pyridinyl)ethoxy group at the 4-position. It is commonly used as a pharmacologically active scaffold in medicinal chemistry, particularly in the development of antidiabetic agents targeting insulin sensitivity.
![5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione](https://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=14211277&t=l)
