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Alternate Names: Amosulalolum
CAS No: 85320-68-9
PubChem CID: 2169
Mol Formula: C18H24N2O5S
Mol Weight: 380.5 g/mol
IUPAC Name: 5-[1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]-2-methylbenzenesulfonamide
API Description: Amosulalol is a medication used mainly for the treatment of high blood pressure (hypertension). It works by blocking both alpha (α₁) and beta (β₁ and β₂) adrenergic receptors, which helps to relax and widen blood vessels while also slowing the heart rate. This combined action reduces blood pressure and decreases the workload on the heart, helping to prevent serious complications such as stroke, heart attack, and kidney problems. In some cases, Amosulalol may also be used for managing angina (chest pain) or as supportive therapy in certain heart failure conditions. It is marketed primarily in Japan under the brand name Lowgan. Common side effects may include dizziness, lightheadedness, fatigue, slow heartbeat, and low blood pressure, especially when standing up quickly.