(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate (CAS No: 376608-71-8) is a key pharmaceutical intermediate used in the synthesis of APIs Tofacitinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Benzeneacetic acid, alpha-hydroxy-, (alphaR)-(1R,2S)-compd. with 2-(3,4-difluorophenyl)cyclopropanamine (1:1); Ticagrelor impurity 83
CAS No: 376608-71-8
PubChem CID: 9944965
Mol Formula: C17H17F2NO3
Mol Weight: 321.32 g/mol
Used in API: Tofacitinib
IUPAC Name: (2R)-2-hydroxy-2-phenylacetic acid;trans-(1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine
API Intermediate Description: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate is primarily used as an intermediate in the synthesis of ticagrelor, a medication used to prevent blood clots. It is also sold for research and development purposes and as a reference standard in forensic and analytical chemistry.
