Benzyloxycarbonyl-l-proline (CAS No: 1148-11-4) is a key pharmaceutical intermediate used in the synthesis of APIs Acalabrutinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: Benzyloxycarbonyl-L-proline, Carbobenzoxy-S-proline
CAS No: 1148-11-4
PubChem CID: 101987
Mol Formula: C13H15NO4
Mol Weight: 249.26 g/mol
Used in API: Acalabrutinib
IUPAC Name: (2S)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
API Intermediate Description: N-Benzyloxycarbonyl-L-proline is used as a protected amino acid in custom peptide synthesis to build specific peptide chains, and as a prolidase inhibitor in biological and pharmaceutical research. It is a key building block that protects the proline residue during peptide assembly and can be used to selectively deprotect and add other amino acids. In research, it has been studied for its ability to inhibit the enzyme prolidase, which is involved in diseases like prolidase deficiency.