1-Methyl-4-pyrazole boronic acid pinacol ester (CAS No: 761446-44-0) is a key pharmaceutical intermediate used in the synthesis of APIs Avapritinib. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS No: 761446-44-0
PubChem CID: 2773987
Mol Formula: C10H17BN2O2
Mol Weight: 208.07 g/mol
Used in API: Avapritinib
IUPAC Name: 1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole
API Intermediate Description: 1-Methyl-4-pyrazole boronic acid pinacol ester is a specialized organic reagent primarily used in Suzuki-Miyaura cross-coupling reactions and transesterification processes within pharmaceutical and chemical synthesis, notably for building complex molecules including aminothiazoles (γ-secretase modulators), JAK2 inhibitors, TGF-β1 signaling inhibitors, and c-Met kinase inhibitors for cancer research.
