(S)-(+)-1,1′-Bi-2-naphthyl-2,2′-diyl hydrogen phosphate (CAS No: 35193-63-6) is a key pharmaceutical intermediate used in the synthesis of APIs Rolapitant hydrochloride. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 1,1'-Binaphthyl-2,2'-diyl hydrogen phosphate, 4-Hydroxydinaphtho(2,1-d:1',2'-f)(1,3,2)dioxaphosphepin 4-oxide
CAS No: 35193-63-6
PubChem CID: 99589
Mol Formula: C20H13O4P
Mol Weight: 348.3 g/mol
Used in API: Rolapitant hydrochloride
IUPAC Name: 13-hydroxy-12,14-dioxa-13λ5-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18, -Show More
API Intermediate Description: (S)-(+)-1,1′-Bi-2-naphthyl-2,2′-diyl hydrogen phosphate is the S-enantiomer of BINOL-derived phosphate, a chiral organophosphate compound. It appears as a white to off-white crystalline powder, sparingly soluble in water but soluble in polar organic solvents such as ethanol, acetonitrile, and dichloromethane.