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Alternate Names: Alkaloid C from cephalotaxus, 3-4-Methyl-(2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioatecephalotaxine
CAS No: 26833-85-2
PubChem CID: 276389
Mol Formula: C28H37NO9
Mol Weight: 531.6 g/mol
IUPAC Name: 1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] -Show More
API Description: Harringtonine is a natural alkaloid extracted from the cephalotaxus (Japanese plum yew) tree. It appears as a white to off-white crystalline powder and is sparingly soluble in water. Harringtonine exhibits antitumor and cytotoxic properties by inhibiting protein synthesis at the ribosomal level, and it is used in research and treatment of certain leukemias, particularly acute myeloid leukemia (AML).