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Alternate Names: Anaptivan, Biociclin, Furoxil, Lifurox, Medoxim, Ultroxim
CAS No: 56238-63-2
PubChem CID: 23670318
Mol Formula: C16H15N4NaO8S
Mol Weight: 446.4 g/mol
Controlled Drug Substance: Yes (Schedule I)
IUPAC Name: sodium;(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Drug Class: Beta-lactams
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Semi-synthetic APIs
API Description: Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.
