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Alternate Names: Elobact, Zinnat, Zinat, Cefuroxime 1-acetoxyethyl ester, Ceftin
CAS No: 64544-07-6
PubChem CID: 6321416
Mol Formula: C20H22N4O10S
Mol Weight: 510.47 g/mol
IUPAC Name: 1-acetyloxyethyl (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carbox -Show More
API Description: An ester prodrug of cefuroxime, this second-generation cephalosporin antibiotic is effective orally and used to treat various infections. Cefuroxime Axetil is a second generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefuroxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefuroxime inhibits bacterial septum and cell wall synthesis formation.
