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Alternate Names: KD025 mesylate
CAS No: 2109704-99-4
Mol Formula: C27H28N6O5S
Mol Weight: 548.6 g/mol
IUPAC Name: 2-[3-[5-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide;methanesulfonic acid
API Description: Belumosudil Mesylate is the mesylate salt form of belumosudil, an orally bioavailable inhibitor of Rho-associated coiled-coil kinase 2 (ROCK2; ROCK-II), with potential immunomodulating activity. Upon oral administration, belumosudil binds to and inhibits the serine/threonine kinase activity of ROCK2.