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Alternate Names: Amipramidin, Guanamprazin, Midamor
CAS No: 2609-46-3
PubChem CID: 16231
Mol Formula: C6H8ClN7O
Mol Weight: 229.64 g/mol
IUPAC Name: 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
Commercial / Development Status: Commercial APIs
Source / Manufacturing Origin: Synthetic APIs
API Description: Amiloride is a potassium-sparing diuretic used to treat hypertension and congestive heart failure. It works by inhibiting sodium channels in the distal nephron, reducing sodium reabsorption and decreasing potassium excretion. Amiloride is a member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid. It has a role as a sodium channel blocker and a diuretic. It is a member of pyrazines, an organochlorine compound, an aromatic amine and a member of guanidines. It is a conjugate base of an amiloride(1+).
