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Alternate Names: Ivadal, Niotal, Zolpidem hemitartrate, Edluar, Tovalt
CAS No: 99294-93-6
PubChem CID: 441338
Mol Formula: C42H48N6O8
Mol Weight: 764.9 g/mol
Controlled Drug Substance: Yes
IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid;N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide
API Description: Zolpidem tartrate is the hemitartrate salt of zolpidem. It contains a zolpidem. Zolpidem Tartrate is the tartrate salt of an imidazopyridine with non-benzodiazepine benzodiazepine-receptor agonist and sedative-hypnotic activities. Zolpidem binds selectively to the alpha 1 subunit of the omega-1 (BZ1) receptor of the gamma-aminobutyric acid type A (GABA-A) receptor-chloride ionophore complex, thereby opening neuronal chloride channels, hyperpolarizing neuronal cell membranes, and inhibiting neuronal firing. In contrast, benzodiazepines non-selectively bind to and activate all omega receptor subtypes, exhibiting anticonvulsant and myorelaxant activities in addition to a sedative-hypnotic activity.
