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Alternate Names: Tucatinib ethanolate (JAN), Irbinitinib hemiethanolate
CAS No: 1429755-56-5
PubChem CID: 162623678
Mol Formula: C54H54N16O5
Mol Weight: 1007.1 g/mol
IUPAC Name: bis(6-N-(4,4-dimethyl-5H-1,3-oxazol-2-yl)-4-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazoline-4,6-diamine);ethanol
API Description: Tucatinib hemiethanolate, marketed as Tukysa, is primarily used in combination with other medications to treat HER2-positive advanced or metastatic breast cancer and colorectal cancer. Specifically, it's used with trastuzumab and capecitabine for breast cancer and with trastuzumab for colorectal cancer, particularly in patients who have previously received other anti-HER2 treatments. It's also approved for treating colorectal cancer that has spread to other parts of the body and is not operable.
