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Alternate Names: jinarc, JYNARQUE, tolvaptanum
CAS No: 150683-30-0
PubChem CID: 216237
Mol Formula: C26H25ClN2O3
Mol Weight: 448.9 g/mol
IUPAC Name: N-[4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)-3-methylphenyl]-2-methylbenzamide
API Description: Tolvaptan is a racemate comprising of equimolar amounts of (R)- and (S)-tolvaptan. It is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency. It has a role as a vasopressin receptor antagonist and an aquaretic. It contains a (S)-tolvaptan and a (R)-tolvaptan.
