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Alternate Names: NGX-424, tezampanelum, Ted-isoquinoline-3-cooh, Tezampanel hydrate
CAS No: 154652-83-2
PubChem CID: 127894
Mol Formula: C13H21N5O2
Mol Weight: 279.34 g/mol
IUPAC Name: (3S,4aR,6R,8aR)-6-[2-(2H-tetrazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid
API Description: Tezampanel is an experimental AMPA/kainate glutamate receptor antagonist developed by Eli Lilly for potential uses in pain, migraine, seizures, cerebral ischemia, and addiction, particularly opioid dependence and withdrawal. Though it reached Phase II clinical trials for migraine and has demonstrated neuroprotective effects against nerve agent-induced brain damage in rats, its development for general use has been discontinued, and it is currently used for research purposes only.
