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Alternate Names: GS-7340 monofumarate, TAF fumarate, HY-15232A
CAS No: 1392275-56-7
PubChem CID: 68516365
Mol Formula: C25H33N6O9P
Mol Weight: 592.5 g/mol
IUPAC Name: (E)-but-2-enedioic acid;propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
API Description: Tenofovir alafenamide monofumarate is an antiviral prodrug used to treat HIV-1 and chronic hepatitis B infections. It delivers the active metabolite tenofovir more efficiently into infected cells, allowing lower dosing and reduced kidney and bone toxicity compared to older formulations. It is often combined with other antiretrovirals in fixed-dose combinations. The monofumarate salt form improves its stability and bioavailability.
