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Alternate Names: JOURNAVX, VX-548, Suzetrigina, VX548
CAS No: 2649467-58-1
PubChem CID: 156445116
Mol Formula: C21H20F5N3O4
Mol Weight: 473.4 g/mol
IUPAC Name: 4-[[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-carbonyl]amino]pyridine-2-carboxamide
API Description: Suzetrigine is under investigation in clinical trial NCT05558410 (Evaluation of Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty). Suzetrigine is an oral, selective sodium channel blocker and non-opioid analgesic that is used to treat moderate or severe pain. Suzetrigine is typically given for only a few days and has not been linked to elevations in serum aminotransferase or alkaline phosphatase levels during therapy or to episodes of clinically apparent liver injury.
