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Alternate Names: Sitagliptin L-malate, UNII-6Q9M3E3GG7, 1240039-02-4
CAS No: 1240039-02-4
PubChem CID: 163203575
Mol Formula: C20H21F6N5O6
Mol Weight: 541.4 g/mol
IUPAC Name: (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one;(2S)-2-hydroxybutanedioic -Show More
API Description: Sitagliptin malate is used for the treatment of type 2 diabetes mellitus. It functions as a DPP-4 (dipeptidyl peptidase-4) inhibitor, similar to sitagliptin hydrochloride, and helps improve blood sugar control by increasing incretin levels. These incretins boost insulin secretion and reduce glucagon release in response to meals, leading to better glucose regulation. The malate salt form is used to enhance the drug’s stability or solubility but does not change its therapeutic effect. Sitagliptin malate is often used alone or with other antidiabetic drugs like metformin.
